Compile Data Set for Download or QSAR
Found 23 Enz. Inhib. hit(s) with Target = 'Lysosomal alpha-glucosidase' and Ligand = 'BDBM50333465'
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)copy SMILEScopy InChI
Affinity DataKi:  3.50E+3nMAssay Description:Competitive inhibition of rat alpha-glucosidase assessed as production of chromogenic p-Nitrphenol measured after 3 mins by HPLC and Michaelis-Menton...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PCKPubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of Wistar rat small intestine maltase after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D21XVSPubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of rat intestinal maltase using moltose as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35VTXPubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of Wistar rat intestinal maltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VRSPubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of rat intestinal brush border membrane maltaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2W2BPubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of rat intestine maltase using maltose as substrate incubated for 10 mins prior to substrate addition measured after 40 mins by glucose ox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63PCDPubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of rat intestinal alpha-glucosidase maltase using maltose as substrate preincubated for 10 mins prior substrate addition measured after 40...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6DC7PubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of rat small intestinal maltase after 30 mins by glucose-oxidase methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6RJCPubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of rat small intestinal maltase after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9J8RPubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of alpha-glucosidase activity of maltase in rat small intestinal brush border membrane fraction using maltose as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K291DPubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of rat intestinal maltaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J1044CPubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of rat intestinal Maltase using maltose as substrate assessed as glucose release after 10 mins by glucose oxidase methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD42C3PubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of rat intestinal maltase using maltose as substrate assessed as D-glucose release from substrate preincubated for 15 mins measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7X24PubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of maltase in human Caco-2 cell model system after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2W2BPubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)copy SMILEScopy InChI
Affinity DataIC50: 6.38E+3nMAssay Description:Inhibition of rat intestinal alpha-glucosidase using p-nitrophenyl- alpha-D-glucopyranoside as substrate preincubated for 5 min before addition of su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75K6S
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)copy SMILEScopy InChI
Affinity DataIC50: 1.61E+4nMAssay Description:Inhibition of maltase in rat intestinal mucosa pre-incubated for 40 mins using maltose substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0VN0PubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)copy SMILEScopy InChI
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of rat intestinal alpha-glucosidase using para-nitrophenyl-alpha-D-glucopyranoside as substrate incubated for 5 min prior to substrate add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q501R
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)copy SMILEScopy InChI
Affinity DataIC50: 2.55E+4nMAssay Description:Inhibition of rat intestinal maltase using maltose as substrate by colorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4K3JPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of human lysosomal alpha-glucosidaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2W2BPubMed
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
North Maharashtra University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of liver glucosidase in Swiss mouse liver extractsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN17CDPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+5nMAssay Description:Inhibition of pure alpha-glucosidase (unknown origin) assessed as para-nitrophenol release at 420 nm ODMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028SV2PubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)copy SMILEScopy InChI
Affinity DataIC50: 4.47E+5nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) pre-incubated for 20 mins before p-nitrophenyl glycoside substrate additionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82C20PubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+6nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using para-nitrophenyl-alpha-D-glucopyranoside as substrate incubated for 15 min prior to substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B91W5