Compile Data Set for Download or QSAR
Found 8 Enz. Inhib. hit(s) with Target = 'Lysyl oxidase homolog 2' and Ligand = 'BDBM50505638'
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis Ltd

Curated by ChEMBL
LigandPNGBDBM50505638(CHEMBL4457578)copy SMILEScopy InChI
Affinity DataKi:  83nMAssay Description:Time-dependent inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells assessed as apparent inh...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GJ2PubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis Ltd

Curated by ChEMBL
LigandPNGBDBM50505638(CHEMBL4457578)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GJ2PubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis Ltd

Curated by ChEMBL
LigandPNGBDBM50505638(CHEMBL4457578)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GJ2PubMed
TargetLysyl oxidase homolog 2(Rattus norvegicus)
Pharmaxis Ltd

Curated by ChEMBL
LigandPNGBDBM50505638(CHEMBL4457578)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant rat LOLX2 using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ev...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GJ2PubMed
TargetLysyl oxidase homolog 2(Mus musculus)
Pharmaxis Ltd

Curated by ChEMBL
LigandPNGBDBM50505638(CHEMBL4457578)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant mouse C-terminal His-tagged LOLX2 (26-776 residues) expressed in mouse myeloma cells using putrescine as substrate preincub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GJ2PubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis Ltd

Curated by ChEMBL
LigandPNGBDBM50505638(CHEMBL4457578)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of LOXL2 in human IMR90 cells using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GJ2PubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis Ltd

Curated by ChEMBL
LigandPNGBDBM50505638(CHEMBL4457578)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human LOXL2 assessed as inhibition of collagen cross linking compound replenishment for 5 days and measured on day 7 by UPL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GJ2PubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis Ltd

Curated by ChEMBL
LigandPNGBDBM50505638(CHEMBL4457578)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells assessed as inhibition of collagen oxid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GJ2PubMed