Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'MAP kinase-interacting serine/threonine-protein kinase 1' and Ligand = 'BDBM375338'
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL
LigandPNGBDBM375338(4-(6-(4-(morpholine-4-carbonyl)phenyl)imidazo[1,2-...)copy SMILEScopy InChI
Affinity DataIC50: 570nMAssay Description:Inhibition of GST-tagged MNK1 (37 to 341 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20004P7PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL
LigandPNGBDBM375338(4-(6-(4-(morpholine-4-carbonyl)phenyl)imidazo[1,2-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP777KUS Patent