Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor' and Ligand = 'BDBM50560816'
LigandPNGBDBM50560816(CHEMBL4756510)copy SMILES
Affinity DataIC50: 2.40nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560816(CHEMBL4756510)copy SMILES
Affinity DataIC50: 189nMAssay Description:Inhibition of CSF1R in mouse NFS-60 cells assessed as reduction in CSF-induced cell proliferation after 72 hrs by CellTiter-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560816(CHEMBL4756510)copy SMILES
Affinity DataKd:  1.90nMAssay Description:Binding affinity to human wild type CSF1R (I564 to S939 residues) expressed in bacterial expression system by kinome scan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed