Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Macrophage migration inhibitory factor' and Ligand = 'BDBM50206030'
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50206030(CHEMBL3957289 | US10336721, Example 22 | US1096819...)copy SMILEScopy InChI
Affinity DataKi:  74nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as borate-enol complex formation using 4-hydroxypheny...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ70S5PubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50206030(CHEMBL3957289 | US10336721, Example 22 | US1096819...)copy SMILEScopy InChI
Affinity DataKi:  74nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB26JTPubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50206030(CHEMBL3957289 | US10336721, Example 22 | US1096819...)copy SMILEScopy InChI
Affinity DataKi:  150nMAssay Description:Data obtained for the Example compounds, obtained using the methods described in Example B.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5JR7US Patent
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50206030(CHEMBL3957289 | US10336721, Example 22 | US1096819...)copy SMILEScopy InChI
Affinity DataKi:  150nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using 4-hydroxyphenyl pyruvic acid (HPP) as substrate, largely following previously report...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RR1WNPPCBioAssay
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50206030(CHEMBL3957289 | US10336721, Example 22 | US1096819...)copy SMILEScopy InChI
Affinity DataKd:  150nMAssay Description:Inhibition of recombinant human MIF tautomerase activity assessed as decrease in formation of borate complex of enol product using 4-HPP as substrate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB26JTPubMed