Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Malate dehydrogenase, mitochondrial' and Ligand = 'BDBM50400094'
TargetMalate dehydrogenase, mitochondrial(Homo sapiens (Human))
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50400094(CHEMBL427092)copy SMILEScopy InChI
Affinity DataKi:  1.90E+3nMAssay Description:Competitive inhibition of MDH2 (unknown origin) using varying NADH level by oxaloacetate-dependent NADH oxidation based Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CCDPubMed
TargetMalate dehydrogenase, mitochondrial(Homo sapiens (Human))
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50400094(CHEMBL427092)copy SMILEScopy InChI
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of MDH2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2DCFPubMed
TargetMalate dehydrogenase, mitochondrial(Homo sapiens (Human))
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50400094(CHEMBL427092)copy SMILEScopy InChI
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of MDH2 (unknown origin) pre-incubated for 1 hr followed by malate and NAD+ additionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CCDPubMed