Compile Data Set for Download or QSAR
Found 48 Enz. Inhib. hit(s) with Target = 'Mast/stem cell growth factor receptor Kit' and Ligand = 'BDBM13530'
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataKi:  14nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z430BPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataKi:  30.7nMAssay Description:Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G44TCQUS Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataKi:  1.40E+4nM ΔG°:  -27.7kJ/molepH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NC5ZHHPCBioAssay
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataKi:  1.50E+4nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NC5ZHHPCBioAssay
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataKi:  7.10E+4nM ΔG°:  -23.7kJ/molepH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NC5ZHHPCBioAssay
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataKi:  8.20E+5nM ΔG°:  -17.6kJ/molepH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NC5ZHHPCBioAssay
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataKi:  2.90E+6nM ΔG°:  -14.5kJ/molepH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NC5ZHHPCBioAssay
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Concentration required to inhibit the activity of K+ stimulated gastric ATPaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4FN0PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 30.7nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R215H9
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of cKIT (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of ATP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9SPDPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of SCF-induced phosphorylation of c-Kit (unknown origin) in MO7e cells by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN44TTPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of c-kit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20001WPPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of c-Kit (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN44TTPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibition of recombinant N-terminal 6x-His-tagged c-KIT (547 to 935 residues)/(694 to 753 residues deletion) (unknown origin) expressed in baculovir...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7M1WPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of c-kit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56JJHPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of KITMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6ZK0PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 97nMAssay Description:Inhibition of human KIT autophosphorylation in human GIST882 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930TC9PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against c-KitMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2WZ9PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirusMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27TTRPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 164nMAssay Description:Inhibition of recombinant C-terminal polyhistidine-tagged human c-KIT expressed in mammalian expression system using Tyr 06 peptide as substrate meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J10591PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 219nMAssay Description:Inhibition of c-kit receptor phosphorylation in M07e cellMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC60TBPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of chimeric PDGF receptor with c-kit cytoplasmic domain phosphorylation in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WW7JD9PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 319nMAssay Description:Inhibition of His-tagged cKIT (unknown origin) expressed in Sf9 cells using Poly(4:1 Glu, Tyr) peptide as substrate after 1 hr by ADP-glo kinase assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3X7KPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Inhibition of human wild type KIT assessed as [gamma33P]ATP incorporation into polyGluTyr after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC61J5PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 400nMMore data for this Ligand-Target Pair
In DepthDetails
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of c-Kit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ67VRPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 413nMAssay Description:Inhibition of c-KitMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC10WVPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 769nMAssay Description:Inhibition of unactivated recombinant human N-terminal 6x-His-tagged c-KIT (547 to 935 residues)/(694 to 753 residues deletion) expressed in baculovi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1B92PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 5.21E+3nMAssay Description:Inhibition of ATP-activated recombinant human N-terminal 6x-His-tagged c-KIT (547 to 935 residues)/(694 to 753 residues deletion) expressed in baculo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1B92PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 9.82E+3nMAssay Description:Inhibition of His-tagged cKIT T670I mutant (544 to 935 residues) (unknown origin) expressed in Sf9 cells using Poly(4:1 Glu, Tyr) peptide as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3X7KPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirusMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27TTRPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataKd:  15nMAssay Description:Binding constant for KIT(V559D) kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RX2PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataEC50:  100nMAssay Description:Inhibition of c-Kit by cellular assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X58QSPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataKd:  71nMAssay Description:Binding constant for KIT(V559D,V654A) kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RX2PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataKd:  14nMAssay Description:Binding affinity to human KIT incubated for 1 hr by kinase binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47Q45PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataKd:  14nMAssay Description:Binding constant for KIT kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RX2PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataKd:  91nMAssay Description:Binding constant for KIT(V559D,V654A) kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataKd:  14nMAssay Description:Binding constant for KIT(L576P) kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataKd:  13nMAssay Description:Binding affinity to KIT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z9851PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataKd:  13nMAssay Description:Binding constant for KIT kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataKd:  560nMAssay Description:Binding constant for KIT(D816H) kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataKd:  2.50E+3nMAssay Description:Binding constant for KIT(V559D,T670I) kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataKd:  15nMAssay Description:Binding constant for KIT(V559D) kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataKd:  820nMAssay Description:Binding constant for KIT(D816V) kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RX2PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataKd:  980nMAssay Description:Binding constant for KIT(D816V) kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataKd:  2.90E+3nMAssay Description:Binding constant for KIT(V559D,T670I) kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RX2PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataKd:  830nMAssay Description:Average Binding Constant for KIT; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69J3TPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataKd:  15nMAssay Description:Binding constant for KIT(A829P) kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed