Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Maternal embryonic leucine zipper kinase' and Ligand = 'BDBM50248924'
TargetMaternal embryonic leucine zipper kinase(Homo sapiens (Human))
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50248924(CHEMBL4099431 | US10981896, Compound 20)copy SMILEScopy InChI
Affinity DataKi:  149nMAssay Description:Inhibition of His6-tagged MELK catalytic domain (1 to 340 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells using Bcl-GL as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833VFFPubMed
TargetMaternal embryonic leucine zipper kinase(Homo sapiens (Human))
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50248924(CHEMBL4099431 | US10981896, Compound 20)copy SMILEScopy InChI
Affinity DataIC50: 1.15E+3nMAssay Description:The top 10 hits from the 1 μM screening and derivatives of MELK-In-1 were subjected to the same assay conditions with varied inhibitor concentra...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X5BWVUS Patent
TargetMaternal embryonic leucine zipper kinase(Homo sapiens (Human))
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50248924(CHEMBL4099431 | US10981896, Compound 20)copy SMILEScopy InChI
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of His6-tagged MELK catalytic domain (1 to 340 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells using Bcl-GL as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833VFFPubMed