Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50139027'
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139027((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Inhibition of [125I]-NDP MSH binding to human Melanocortin 4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2NWTPubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139027((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)copy SMILEScopy InChI
Affinity DataKi:  34nMAssay Description:Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139027((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)copy SMILEScopy InChI
Affinity DataKi:  52nMAssay Description:Displacement of [125I]NDP-MSH from HEK293 cells expressing human melanocortin-4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251HPHPubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139027((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)copy SMILEScopy InChI
Affinity DataEC50:  14nMAssay Description:Agonistic potency of the compound towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5F21PubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139027((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)copy SMILEScopy InChI
Affinity DataEC50:  240nMAssay Description:Effective concentration against cAMP release in CHO cells expressing human melanocortin-4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251HPHPubMed