Found 8 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Ligand = 'BDBM50052256'
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The Royal Danish School of Pharmacy
Curated by ChEMBL
The Royal Danish School of Pharmacy
Curated by ChEMBL
Affinity DataKi: 2.50E+4nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The Royal Danish School of Pharmacy
Curated by ChEMBL
The Royal Danish School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:The compound was tested for inhibitory effect on second messenger formation in BHK cells expressing mGluR1aMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibitory activity of the compound against Metabotropic glutamate receptor 1 in the rat LLC-PK1/HEK 293 cells.More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The Royal Danish School of Pharmacy
Curated by ChEMBL
The Royal Danish School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of mGluR1a receptorMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The Royal Danish School of Pharmacy
Curated by ChEMBL
The Royal Danish School of Pharmacy
Curated by ChEMBL
In DepthDetails
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The Royal Danish School of Pharmacy
Curated by ChEMBL
The Royal Danish School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Antagonist activity at mGlu1 receptorMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The Royal Danish School of Pharmacy
Curated by ChEMBL
The Royal Danish School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibitory activity against mGluR1 receptorMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The Royal Danish School of Pharmacy
Curated by ChEMBL
The Royal Danish School of Pharmacy
Curated by ChEMBL
Affinity DataEC50: >3.00E+5nMAssay Description:The compound was tested for effect on second messenger formation in BHK cells expressing mGluR1aMore data for this Ligand-Target Pair