Compile Data Set for Download or QSAR
Found 8 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Ligand = 'BDBM50052256'
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052256((S)-3-(amino(carboxy)methyl)bicyclo[1.1.1]pentane-...)copy SMILEScopy InChI
Affinity DataKi:  2.50E+4nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ090QPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052256((S)-3-(amino(carboxy)methyl)bicyclo[1.1.1]pentane-...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:The compound was tested for inhibitory effect on second messenger formation in BHK cells expressing mGluR1aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2NDJPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Parc Club Orsay Université

Curated by ChEMBL
LigandPNGBDBM50052256((S)-3-(amino(carboxy)methyl)bicyclo[1.1.1]pentane-...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibitory activity of the compound against Metabotropic glutamate receptor 1 in the rat LLC-PK1/HEK 293 cells.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1HRDPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052256((S)-3-(amino(carboxy)methyl)bicyclo[1.1.1]pentane-...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of mGluR1a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95PHPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052256((S)-3-(amino(carboxy)methyl)bicyclo[1.1.1]pentane-...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMMore data for this Ligand-Target Pair
In DepthDetails
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052256((S)-3-(amino(carboxy)methyl)bicyclo[1.1.1]pentane-...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Antagonist activity at mGlu1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5W7QPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052256((S)-3-(amino(carboxy)methyl)bicyclo[1.1.1]pentane-...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibitory activity against mGluR1 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2416W6XPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052256((S)-3-(amino(carboxy)methyl)bicyclo[1.1.1]pentane-...)copy SMILEScopy InChI
Affinity DataEC50: >3.00E+5nMAssay Description:The compound was tested for effect on second messenger formation in BHK cells expressing mGluR1aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2NDJPubMed