Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM50121641'
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50121641(CHEMBL3616859)copy SMILEScopy InChI
Affinity DataKi:  339nMAssay Description:Displacement of [3H]-459477 from human recombinant mGlu2 receptor expressed in AV12 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1ST0PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50121641(CHEMBL3616859)copy SMILEScopy InChI
Affinity DataEC50:  74nMAssay Description:Agonist activity at human recombinant mGlu2 receptor expressed in AV12 cells assessed as inhibition of forskolin-stimulated cAMP production after 1 h...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1ST0PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50121641(CHEMBL3616859)copy SMILEScopy InChI
Affinity DataEC50:  242nMAssay Description:Agonist activity at human recombinant mGlu2 receptor expressed in AV12 cells assessed as stimulation of Ca2+ mobilization after 1 hr by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1ST0PubMed