Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM50167034'
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50167034((1S,2S,4S,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...)copy SMILEScopy InChI
Affinity DataKi:  635nMAssay Description:Displacement of [3H]-341495 binding to membranes expressing recombinant human Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0TDRPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50167034((1S,2S,4S,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...)copy SMILEScopy InChI
Affinity DataEC50:  29nMAssay Description:Agonist activity at human mGlu2 receptor expressed in golden Syrian hamster AV12 cells coexpressing EAAT1 after 20 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20003G4PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50167034((1S,2S,4S,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...)copy SMILEScopy InChI
Affinity DataEC50:  45nMAssay Description:Evaluation of the functional effect on cAMP responses in RGT cells expressing human mGlu2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0TDRPubMed