Found 11 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50105838' 
Affinity DataKi: 32nMAssay Description:Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 33nMAssay Description:Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 162nMAssay Description:Displacement of [3H]MPEP from human cloned mGluR5 receptor expressed in CHO-T-Rex cells after 60 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 162nMAssay Description:Displacement of [3H]MPEP from human mGlu5 receptor expressed in CHO-TREx cell membranes after 60 mins by liquid scintillation spectrometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 162nMAssay Description:Displacement of [3H]MPEP from human mGlu5 receptor expressed in CHO-TREx cell membranes after 60 mins by liquid scintillation spectrometric analysisMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
University of Modena and Reggio Emilia
Curated by ChEMBL
University of Modena and Reggio Emilia
Curated by ChEMBL
Affinity DataKi: 313nMAssay Description:Displacement of [3H]MPEP from mGluR5 receptor in Sprague-Dawley rat forebrain membrane after 60 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Negative allosteric modulatory activity at human cloned mGluR5 receptor expressed in CHO-T-Rex cells assessed as inhibiton of quisqualate-induced cal...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
University of Modena and Reggio Emilia
Curated by ChEMBL
University of Modena and Reggio Emilia
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Displacement of [3H]-MPEP from rat mGlu5 receptor expressed in HEK293 cell membranes after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Displacement of [3H]-MPEP from human mGlu5 receptor expressed in HEK293 cell membranes after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
