Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50123005'
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50123005(2-(3-Methoxy-phenylethynyl)-6-methyl-pyridine | 2-...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Displacement of [3H]ABP688 from human mGluR5 receptor expressed in L (tk-) cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50123005(2-(3-Methoxy-phenylethynyl)-6-methyl-pyridine | 2-...)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Displacement of [3H]ABP688 from mGluR5 in rat brain membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50123005(2-(3-Methoxy-phenylethynyl)-6-methyl-pyridine | 2-...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Concentration required for 50% growth inhibition of rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assayMore data for this Ligand-Target Pair