Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50236748'
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236748(CHEMBL4081358)copy SMILEScopy InChI
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Gedeon Richter Plc

Curated by ChEMBL
LigandPNGBDBM50236748(CHEMBL4081358)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Negative allosteric modulation of human mGluR5a expressed in CHO cells assessed as reduction in DHPG-induced cytosolic Ca2+ influx after 10 to 20 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R05PubMed