Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Methionine aminopeptidase 2' and Ligand = 'BDBM401308'
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM401308(US10005756, Compound A79)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of MetAP2 in HUVEC assessed as reduction in viability incubated for 3 days by CyQUANT Direct Cell proliferation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4MXQPubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM401308(US10005756, Compound A79)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of MetAP2 in HUVEC assessed as reduction in viability incubated for 3 days by CyQUANT Direct Cell proliferation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4MXQPubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM401308(US10005756, Compound A79)copy SMILEScopy InChI
Affinity DataIC50: 92nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and MnCl2 as co-facor preincubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4MXQPubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM401308(US10005756, Compound A79)copy SMILEScopy InChI
Affinity DataIC50: 92nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and MnCl2 as co-facor preincubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4MXQPubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM401308(US10005756, Compound A79)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:The MetAP-2 activity is determined by coupling enzymatic reactions. The tripeptide Met-Arg-Ser (MAS) is employed as substrate. The methionine liberat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KSKUS Patent