Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Mineralocorticoid receptor' and Ligand = 'BDBM50235975'
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50235975(CHEMBL4079083)copy SMILEScopy InChI
Affinity DataIC50: 1.18E+3nMAssay Description:Displacement of [3H]-aldosterone from human GST-tagged MR ligand binding domain after 4 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V1277HPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50235975(CHEMBL4079083)copy SMILEScopy InChI
Affinity DataIC50: 1.97E+3nMAssay Description:Antagonist activity at human GAL4-DBD fused MR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V1277HPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50235975(CHEMBL4079083)copy SMILEScopy InChI
Affinity DataIC50: 1.97E+3nMAssay Description:Antagonist activity at Gal4-fused MR LBD (unknown origin) expressed in human Huh7 cells assessed as inhibition of aldosterone-induced transcriptional...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7XXBPubMed