Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 1' and Ligand = 'BDBM50229978'
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50229978(5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOL...)copy SMILEScopy InChI
Affinity DataKi:  310nMAssay Description:Binding affinity to ERK2Checked by AuthorMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50229978(5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOL...)copy SMILEScopy InChI
Affinity DataKi:  310nMAssay Description:Inhibition of ERK2Checked by AuthorMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50229978(5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOL...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Binding affinity to non-phosphorylated full length N-terminal His6-tagged/SUMO-fused ERK2 (1 to 360 residues) (unknown origin) by isothermal titratio...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50229978(5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOL...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory activity against human ERK2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50229978(5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOL...)copy SMILEScopy InChI
Affinity DataKd:  850nMAssay Description:Binding affinity to ERK2 (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair