Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50175755'
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50175755(2-(4-(5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorop...)copy SMILEScopy InChI
Affinity DataIC50: 0.840nMAssay Description:Inhibition of P38 alpha MAPKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4QH8PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50175755(2-(4-(5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorop...)copy SMILEScopy InChI
Affinity DataIC50: 3.75nMAssay Description:Inhibition of TNF alpha release in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4QH8PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50175755(2-(4-(5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorop...)copy SMILEScopy InChI
Affinity DataIC50: 79.1nMAssay Description:Inhibition of LPS stimulated TNF alpha release in whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4QH8PubMed