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Affinity DataKi: 2.90nMAssay Description:Inhibition of p38alpha kinaseMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
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In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMedDrugBank
MMDB
PDB
![3D 3D](/images/Docked_3d.png)
Affinity DataKi: 5.80nMAssay Description:Binding affinity to p38alphaMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
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UniProtKB/SwissProt
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In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q27H1JQCPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q27H1JQCPubMedDrugBank
MMDB
PDB
![3D 3D](/images/Docked_3d.png)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of p38alpha kinase-dependent HSP-27 phosphorylation in human U937 cellsMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
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UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMedDrugBank
MMDB
PDB
![3D 3D](/images/Docked_3d.png)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of p38alpha assessed as phosphorylation FITC-labeled Hsp27 after 60 mins by fluorescence based cascade assayMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
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UniProtKB/SwissProt
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In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2SB46R2PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2SB46R2PubMedDrugBank
MMDB
PDB
![3D 3D](/images/Docked_3d.png)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of p38alpha assessed as phosphorylation FITC-labeled Hsp27 after 60 mins by fluorescence based cascade assayMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2SB46R2PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2SB46R2PubMedDrugBank
MMDB
PDB
![3D 3D](/images/Docked_3d.png)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of p38alpha assessed as phosphorylation FITC-labeled Hsp27 after 60 mins by fluorescence based cascade assayMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2SB46R2PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2SB46R2PubMedDrugBank
MMDB
PDB
![3D 3D](/images/Docked_3d.png)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q20Z73F0PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q20Z73F0PubMedDrugBank
MMDB
PDB
![3D 3D](/images/Docked_3d.png)
Affinity DataIC50: 17nMAssay Description:Inhibition of p38alpha kinase in human monocytesMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMedDrugBank
MMDB
PDB
![3D 3D](/images/Docked_3d.png)
Affinity DataKd: 2.80nMAssay Description:Binding affinity to wild type human biotin labelled p38 alpha (9 to 352 residues) expressed in sf21 insect cells assessed as dissociation rate consta...More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
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UniProtKB/SwissProt
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In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2RV0QVZPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2RV0QVZPubMedDrugBank
MMDB
PDB
![3D 3D](/images/Docked_3d.png)
Affinity DataKd: 2.5nMAssay Description:In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholineMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2RV0QVZPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2RV0QVZPubMedDrugBank
MMDB
PDB
![3D 3D](/images/Docked_3d.png)
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