Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50363303'
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50363303(CHEMBL1945721)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human recombinant P38alpha assessed as inhibition of GST-tagged ATF2 phosphorylation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ598PPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50363303(CHEMBL1945721)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of P38alpha in human whole blood assessed as inhibition of TNF-alpha-induced IL-8 production incubated for 1 hr prior to TNFalpha challeng...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ598PPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50363303(CHEMBL1945721)copy SMILEScopy InChI
Affinity DataIC50: 9.80nMAssay Description:Inhibition of P38alpha in human whole blood assessed as inhibition of LPS-induced MK2 phosphorylation incubated for 30 mins prior to LPS challenge me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ598PPubMed