Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50392148'
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University

Curated by ChEMBL
LigandPNGBDBM50392148(CHEMBL2152778)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of p38alpha by immunosorbent based kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4JTJPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University

Curated by ChEMBL
LigandPNGBDBM50392148(CHEMBL2152778)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Competitive inhibition of p38alpha MAP kinase (unknown origin) in presence of 100 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81H2CPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University

Curated by ChEMBL
LigandPNGBDBM50392148(CHEMBL2152778)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of p38alpha-dependent TNFalpha production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4JTJPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University

Curated by ChEMBL
LigandPNGBDBM50392148(CHEMBL2152778)copy SMILEScopy InChI
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of p38alpha MAP kinase in human whole blood assessed as inhibition of LPS-induced TNFalpha release by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81H2CPubMed