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Compile Data Set for Download or QSAR
Found
1
Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14 [G110A]' and Ligand = 'BDBM15244'
Target
Mitogen-activated protein kinase 14 [G110A]
(Mus musculus (mouse))
Merck Research Laboratories
Ligand
BDBM15244
(5-(2,6-dichlorophenyl)-2-(2,4-difluorophenyl)sulfa...)
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Affinity Data
IC50: 34nM
pH: 7.0 T: 2°C
Assay Description:
The biochemical activity of compounds was determined by incubation with wild-type or mutant p38alpha enzymes, and substrates in the presence ATP/[gam...
More data for this Ligand-Target Pair
Target Info
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Article
BindingDB Entry DOI:
10.7270/Q2SX6BF9
PubMed
PDB
3D Structure (crystal)