Compile Data Set for Download or QSAR
Found 10 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 9' and Ligand = 'BDBM13336'
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of c-Jun N-terminal kinase 2-beta 1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27D2T9NPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of c-Jun N-terminal kinase 2-alpha 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81C8DPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM59DGPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of c-Jun N-terminal kinase 2-alpha 2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81C8DPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of c-Jun N-terminal kinase 2-beta 2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27D2T9NPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human mitogen-activated protein kinase 9 (JNK 2) at 100 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56J8XPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)copy SMILEScopy InChI
Affinity DataKd:  130nMAssay Description:Binding constant for JNK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)copy SMILEScopy InChI
Affinity DataKd:  130nMAssay Description:Binding constant for full-length JNK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RX2PubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)copy SMILEScopy InChI
Affinity DataKd:  130nMpH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NC5ZHHPCBioAssay
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)copy SMILEScopy InChI
Affinity DataKd:  95nMAssay Description:Average Binding Constant for JNK2; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69J3TPubMed