Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 12' and Ligand = 'BDBM50271220'
TargetMitogen-activated protein kinase kinase kinase 12(Homo sapiens (Human))
WuXi AppTec Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50271220(CHEMBL3718265)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Binding affinity to N-terminally GST-tagged wild type human DLK (1 to 520 residues) expressed in sf21 insect cells using N-terminally His-tagged MKK4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639S7KPubMed
TargetMitogen-activated protein kinase kinase kinase 12(Homo sapiens (Human))
WuXi AppTec Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50271220(CHEMBL3718265)copy SMILEScopy InChI
Affinity DataIC50: 302nMAssay Description:Inhibition of doxycycline inducible human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-bas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639S7KPubMed