Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase kinase 1' and Ligand = 'BDBM459439'
LigandPNGBDBM459439(US10752635, Example 1, Peak 2 | US11492354, Exampl...)copy SMILEScopy InChI
Affinity DataKi:  1.80nMAssay Description:Vasopressin V2 receptor antagonistic activity in vivo in anesthetized ratsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM459439(US10752635, Example 1, Peak 2 | US11492354, Exampl...)copy SMILEScopy InChI
Affinity DataKi: <100nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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BindingDB Entry DOI: 10.7270/Q2Q81HW4US Patent
LigandPNGBDBM459439(US10752635, Example 1, Peak 2 | US11492354, Exampl...)copy SMILEScopy InChI
Affinity DataKi: <100nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61J7DUS Patent
LigandPNGBDBM459439(US10752635, Example 1, Peak 2 | US11492354, Exampl...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Compound was evaluated for the inhibition of Escherichia coli Thymidylate SynthaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails