Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase kinase 1' and Ligand = 'BDBM466704'
LigandPNGBDBM466704(US10800761, Example 23 | US11731958, Example 23)copy SMILEScopy InChI
Affinity DataKi:  1.70nMAssay Description:In vitro inhibition of human carbonic anhydrase II (0.1 nM).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM466704(US10800761, Example 23 | US11731958, Example 23)copy SMILEScopy InChI
Affinity DataKi: <100nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair
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BindingDB Entry DOI: 10.7270/Q2K35XQDUS Patent
LigandPNGBDBM466704(US10800761, Example 23 | US11731958, Example 23)copy SMILEScopy InChI
Affinity DataKi: <100nMMore data for this Ligand-Target Pair
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BindingDB Entry DOI: 10.7270/Q2GF0ZNJ
LigandPNGBDBM466704(US10800761, Example 23 | US11731958, Example 23)copy SMILEScopy InChI
Affinity DataKi:  276nMAssay Description:Inhibitory activity against human carbonic anhydrase II using pH stat assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM466704(US10800761, Example 23 | US11731958, Example 23)copy SMILEScopy InChI
Affinity DataIC50: 1.17E+3nMAssay Description:In vitro for inhibition of rat HMG-CoA reductase.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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