Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Monoglyceride lipase' and Ligand = 'BDBM50132713'
TargetMonoglyceride lipase(Homo sapiens (Human))
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50132713(Arachidonic acid derivative | CHEMBL113262 | Methy...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Reversible inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z74Z4PubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50132713(Arachidonic acid derivative | CHEMBL113262 | Methy...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Reversible inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid after 30 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z74Z4PubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50132713(Arachidonic acid derivative | CHEMBL113262 | Methy...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Reversible inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid after 60 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z74Z4PubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50132713(Arachidonic acid derivative | CHEMBL113262 | Methy...)copy SMILEScopy InChI
Affinity DataIC50: 26.3nMAssay Description:Inhibition of human MGL activity using [3H]2-oleoylglycerol substrate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319X48PubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50132713(Arachidonic acid derivative | CHEMBL113262 | Methy...)copy SMILEScopy InChI
Affinity DataIC50: 26.3nMAssay Description:Inhibition of human MGLMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7B59PubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50132713(Arachidonic acid derivative | CHEMBL113262 | Methy...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Reversible inhibition of human recombinant MAGL using 2-arachidonoylglycerol substrate assessed as arachidonic acid after 90 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z74Z4PubMed