Found 54 Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM21864' 
Affinity DataKi: 0.360nMAssay Description:Displacement of [3H]- diprenorphine from mu-W318A-receptor expressed in HEK 293More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Antagonist activity on agonist stimulated [35S]GTP-gamma-S, binding in guinea pig caudate membranes (10 uM DAMGO as the agonist ligand for mu-recepto...More data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:The ability of compound to inhibit [35S]GTP-delta-S binding in guinea pig caudate stimulated by DAMGO (Opioid receptor mu 1) antagonistMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Ability to inhibit GTP-gamma-S binding to Opioid receptor mu 1 of guinea pig caudate.More data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Ability to displace [3H]DADL from delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Apparent binding affinity of compound was determined by antagonism towards Opioid receptor mu 1 in [35S]GTP-gamma-S, binding assay in guinea pig caud...More data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Compound was evaluated for its ability to displace [3H]DAMGO in C6 glioma cells expressing the cloned Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:The compound was evaluated for binding affinity against opioid receptor mu in guinea pig brain membranes using [3H]- DAMGO as ligandMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:The opioid receptor affinity(Ki) was evaluated by competition with [3H]DAMGO (mu) on guinea pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Binding affinity against mu-opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Binding affinity was measured by the displacement of [3H]- DAMGO in guinea pig brain membrane of Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Binding affinity was measured by the displacement of [3H]- EK in guinea pig brain membrane of Opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Compound was evaluated for binding affinity at Opioid receptor mu 1 in guinea pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Tested for binding affinity against mu opioid receptor fby displacing [3H]- DAMGO radioligand from rat brain membrane preparationsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute
Curated by ChEMBL
Rensselaer Polytechnic Institute
Curated by ChEMBL
Affinity DataKi: 5.30nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 6.10nMAssay Description:Binding affinity against Opioid receptor mu 1 binding in ICR mouse brain membranes using the radioligand [3H][Ala2,Glyol5]enkephalinMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute
Curated by ChEMBL
Rensselaer Polytechnic Institute
Curated by ChEMBL
Affinity DataKi: 6.30nMAssay Description:Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute
Curated by ChEMBL
Rensselaer Polytechnic Institute
Curated by ChEMBL
Affinity DataKi: 6.30nMAssay Description:Binding affinity for human Opioid receptor mu 1 transfected into chinese hamster ovary cells by displacing [3H]DAMGO radioligandMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute
Curated by ChEMBL
Rensselaer Polytechnic Institute
Curated by ChEMBL
TargetMu-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute
Curated by ChEMBL
Rensselaer Polytechnic Institute
Curated by ChEMBL
Affinity DataKi: 6.30nMAssay Description:Displacement of [3H]DAMGO from human recombinant Opioid receptor mu 1 on CHO cell membranes.More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute
Curated by ChEMBL
Rensselaer Polytechnic Institute
Curated by ChEMBL
Affinity DataKi: 6.30nMAssay Description:Inhibition of [3H]DAMGO binding to human Mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute
Curated by ChEMBL
Rensselaer Polytechnic Institute
Curated by ChEMBL
Affinity DataKi: 6.30nMAssay Description:Maximum % effect of standard (DAMGO) was reported against Opioid receptor mu 1More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute
Curated by ChEMBL
Rensselaer Polytechnic Institute
Curated by ChEMBL
Affinity DataKi: 7.20nMAssay Description:Binding affinity determined against Opioid receptor mu 1 from human cloned receptorMore data for this Ligand-Target Pair
Affinity DataKi: 12.7nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Binding affinity at mu opioid receptor 1 in rat brain membrane by [3H]DAMGO displacement.More data for this Ligand-Target Pair
Affinity DataKi: 13.5nMAssay Description:Displacement of [3H]- diprenorphine from mu-K303E-receptor expressed in HEK 293More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute
Curated by ChEMBL
Rensselaer Polytechnic Institute
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Tested for binding activity against mu opioid receptor using [3H]DAMGO ligandMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Binding affinity of compound was determined against Opioid receptor mu 1 from native receptor in guinea pigMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Binding affinity against Opioid receptor mu 1 using [3H][D-Ala2, MePhe4, Gly-ol5]-enkephalin as radioligandMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute
Curated by ChEMBL
Rensselaer Polytechnic Institute
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat cerebrum membranesMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat cerebellum membraneMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute
Curated by ChEMBL
Rensselaer Polytechnic Institute
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Displacement of [3H]DAMGO from Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Binding affinity towards Opioid receptor mu 1 by the displacement of [3H]DAMGO radioligand in rat brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Ability to displace [3H]DAMGO from mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Binding affinity to guinea pig mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Binding affinity to mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Compound was tested for its ability to displace [3H]DAMGO from mu receptor in rat brain.More data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Binding affinity to Opioid receptor mu 1 by using [3H]DAMGO as a radioligand from guinea pigMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Compound was evaluated for the binding affinity towards mu opioid receptor in rat brain homogenates using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 33.9nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 34.4nMAssay Description:Displacement of [3H]- diprenorphine from mu-receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of [3H]DAMGO from Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute
Curated by ChEMBL
Rensselaer Polytechnic Institute
Curated by ChEMBL
Affinity DataKi: 99nMAssay Description:Binding affinity to mu opioid receptor was measured using [3H]DAMGOMore data for this Ligand-Target Pair
Affinity DataKi: 99nMAssay Description:Binding affinity for Opioid receptor mu 1 was determined by inhibition of binding of [3H]DAMGO (1.4-3 nM) to rat brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 151nMAssay Description:Binding affinity at Opioid receptor mu 1 by displacement of [3H]DAMGO in rat brain membraneMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute
Curated by ChEMBL
Rensselaer Polytechnic Institute
Curated by ChEMBL
Affinity DataKi: 151nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
