Compile Data Set for Download or QSAR
Found 15 Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50381677'
TargetMu-type opioid receptor(MOUSE)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50381677(CHEMBL1256748 | U-69593)copy SMILEScopy InChI
Affinity DataKi:  1.20nMAssay Description:Binding affinity against opioid receptor by displacing radioligand [3HlU69,593More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M32WD4PubMed
TargetMu-type opioid receptor(MOUSE)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50381677(CHEMBL1256748 | U-69593)copy SMILEScopy InChI
Affinity DataKi:  548nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain membranes without cerebellum after 1 hr by liquid scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348MPCPubMed
TargetMu-type opioid receptor(GUINEA PIG)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50381677(CHEMBL1256748 | U-69593)copy SMILEScopy InChI
Affinity DataKi:  692nMAssay Description:Displacement of radiolabeled DAMGO from mu opioid receptor in Hartley guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9RXFPubMed
TargetMu-type opioid receptor(MOUSE)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50381677(CHEMBL1256748 | U-69593)copy SMILEScopy InChI
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]DAMGO from mouse whole brain MORMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53NFKPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50381677(CHEMBL1256748 | U-69593)copy SMILEScopy InChI
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity determined against Opioid receptor mu 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08QQPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50381677(CHEMBL1256748 | U-69593)copy SMILEScopy InChI
Affinity DataKi:  1.15E+3nMAssay Description:Displacement of [3H]DAMGO from human recombinant Opioid receptor mu 1 on CHO cell membranes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945F9PubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50381677(CHEMBL1256748 | U-69593)copy SMILEScopy InChI
Affinity DataKi:  1.15E+3nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cell membranes incubated for 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X58ZXPubMed
TargetMu-type opioid receptor(GUINEA PIG)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50381677(CHEMBL1256748 | U-69593)copy SMILEScopy InChI
Affinity DataKi:  1.88E+3nMAssay Description:Binding affinity of compound was determined against Opioid receptor mu 1 from native receptor in guinea pigMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08QQPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50381677(CHEMBL1256748 | U-69593)copy SMILEScopy InChI
Affinity DataKi: >2.00E+3nMAssay Description:Displacement of [3H]DAMGO from human recombinant opioid mu receptor expressed in CHO cell membranes after 2 hrs by liquid scintillation counting meth...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0W6WPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50381677(CHEMBL1256748 | U-69593)copy SMILEScopy InChI
Affinity DataKi:  2.37E+3nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO cells membrane after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC03ZQPubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50381677(CHEMBL1256748 | U-69593)copy SMILEScopy InChI
Affinity DataKi:  7.25E+3nMAssay Description:Binding affinity at Opioid receptor mu 1 by displacement of [3H]DAMGO in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639QGWPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50381677(CHEMBL1256748 | U-69593)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DAMGO from human MOP receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0V9TPubMed
TargetMu-type opioid receptor(GUINEA PIG)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50381677(CHEMBL1256748 | U-69593)copy SMILEScopy InChI
Affinity DataIC50: 1.76E+3nMAssay Description:Tested for inhibitory concentration against [3H]DAMGO binding at sites of mu-opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513ZVFPubMed
TargetMu-type opioid receptor(GUINEA PIG)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50381677(CHEMBL1256748 | U-69593)copy SMILEScopy InChI
Affinity DataIC50: 1.76E+3nMAssay Description:Inhibitory concentration was determined against Opioid receptor mu 1 using [3H]- DAMGO radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4KFBPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50381677(CHEMBL1256748 | U-69593)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding to recombinant human Opioid receptor mu 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945F9PubMed