Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Multidrug resistance-associated protein 1' and Ligand = 'BDBM50140825'
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50140825(4-{4-[2-(3,4-Difluoro-phenyl)-ethyl]-piperazin-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibitory activity against human transporter MRP1 (Multidrug resistance associated protein 1) expressed in COR.L23/R cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VH0PubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50140825(4-{4-[2-(3,4-Difluoro-phenyl)-ethyl]-piperazin-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibitory concentration against multidrug resistance associated protein 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34X15PubMed
TargetMultidrug resistance-associated protein 1(Mus musculus)
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50140825(4-{4-[2-(3,4-Difluoro-phenyl)-ethyl]-piperazin-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 3.02E+4nMAssay Description:Inhibitory concentration to inhibit MRP1 in CYP 3A4 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VH0PubMed
TargetMultidrug resistance-associated protein 1(Mus musculus)
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50140825(4-{4-[2-(3,4-Difluoro-phenyl)-ethyl]-piperazin-1-y...)copy SMILEScopy InChI
Affinity DataEC50:  97nMAssay Description:Effective concentration of the compound to inhibit MRP1 in potentiation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VH0PubMed