Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Multidrug resistance-associated protein 1' and Ligand = 'BDBM67690'
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Wake Forest University School of Medicine

Curated by ChEMBL
LigandPNGBDBM67690(1,4-bis[2-(2-hydroxyethylamino)ethylamino]-5,8-bis...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:TP_TRANSPORTER: cell accumulation in MCF7/MRP1-M24 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5PDSPubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Wake Forest University School of Medicine

Curated by ChEMBL
LigandPNGBDBM67690(1,4-bis[2-(2-hydroxyethylamino)ethylamino]-5,8-bis...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:TP_TRANSPORTER: cell accumulation in MCF7/MRP1-M6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5PDSPubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Wake Forest University School of Medicine

Curated by ChEMBL
LigandPNGBDBM67690(1,4-bis[2-(2-hydroxyethylamino)ethylamino]-5,8-bis...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:TP_TRANSPORTER: cell accumulation in MCF7/MRP1-10 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5PDSPubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Wake Forest University School of Medicine

Curated by ChEMBL
LigandPNGBDBM67690(1,4-bis[2-(2-hydroxyethylamino)ethylamino]-5,8-bis...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of MRP1 in human 2008/MRP1 cells assessed as reduction in cell viability after 5 days by MTS/PMS assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4T5QPubMed