Found 7 Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Ligand = 'BDBM50030223' TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£ di Camerino
Curated by ChEMBL
Universit£ di Camerino
Curated by ChEMBL
Affinity DataKi: 0.912nMAssay Description:Displacement of [3H]NMS from human M1 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£ di Camerino
Curated by ChEMBL
Universit£ di Camerino
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Antagonist activity at human M1 receptor expressed in HEK293T cells assessed as inhibition of carbachol-induced response by BRET based beta-arrestin ...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£ di Camerino
Curated by ChEMBL
Universit£ di Camerino
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:Antagonist activity at human M1 receptor expressed in HEK293T cells assessed as inhibition of carbachol-induced response by BRET based Gq protein eng...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£ di Camerino
Curated by ChEMBL
Universit£ di Camerino
Curated by ChEMBL
Affinity DataIC50: 741nMAssay Description:Antagonist activity at human M1 receptor expressed in HEK293T cells assessed as inhibition of carbachol-induced response by BRET based Gq protein act...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£ di Camerino
Curated by ChEMBL
Universit£ di Camerino
Curated by ChEMBL
Affinity DataEC50: 174nMAssay Description:Agonist activity at human M1 receptor expressed in HEK293T cells by BRET based beta-arrestin engagement assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£ di Camerino
Curated by ChEMBL
Universit£ di Camerino
Curated by ChEMBL
Affinity DataEC50: 42nMAssay Description:Agonist activity at human M1 receptor expressed in HEK293T cells by BRET based Gq protein activation assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£ di Camerino
Curated by ChEMBL
Universit£ di Camerino
Curated by ChEMBL
Affinity DataEC50: 166nMAssay Description:Agonist activity at human M1 receptor expressed in HEK293T cells by BRET based Gq protein engagement assayMore data for this Ligand-Target Pair
