Compile Data Set for Download or QSAR
Found 7 Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Ligand = 'BDBM325621'
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))TBA
LigandPNGBDBM325621(US9636336, Example 11 | US9636336, Example 65 | US...)copy SMILEScopy InChI
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48WCPubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))TBA
LigandPNGBDBM325621(US9636336, Example 11 | US9636336, Example 65 | US...)copy SMILEScopy InChI
Affinity DataKi:  6.31nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48WCPubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))TBA
LigandPNGBDBM325621(US9636336, Example 11 | US9636336, Example 65 | US...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SH5US Patent
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))TBA
LigandPNGBDBM325621(US9636336, Example 11 | US9636336, Example 65 | US...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SH5US Patent
LigandPNGBDBM325621(US9636336, Example 11 | US9636336, Example 65 | US...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Antagonist activity at muscarinic M3 receptor in rat trachea assessed as inhibition of carbachol-induced contractionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48WCPubMed
LigandPNGBDBM325621(US9636336, Example 11 | US9636336, Example 65 | US...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Antagonist activity at muscarinic M3 receptor in rat trachea assessed as inhibition of carbachol-induced contractionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN48WCPubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))TBA
LigandPNGBDBM325621(US9636336, Example 11 | US9636336, Example 65 | US...)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SH5US Patent