Found 6 Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M4' and Ligand = 'BDBM50030223' TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Universit£ di Camerino
Curated by ChEMBL
Universit£ di Camerino
Curated by ChEMBL
Affinity DataKi: 0.891nMAssay Description:Displacement of [3H]NMS from human M4 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Universit£ di Camerino
Curated by ChEMBL
Universit£ di Camerino
Curated by ChEMBL
Affinity DataIC50: 145nMAssay Description:Antagonist activity at human M4 receptor expressed in HEK293T cells assessed as inhibition of carbachol-induced response by beta-arrestin engagement ...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Universit£ di Camerino
Curated by ChEMBL
Universit£ di Camerino
Curated by ChEMBL
Affinity DataIC50: 407nMAssay Description:Antagonist activity at human M4 receptor expressed in HEK293T cells assessed as inhibition of carbachol-induced response by BRET based Gq protein eng...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Universit£ di Camerino
Curated by ChEMBL
Universit£ di Camerino
Curated by ChEMBL
Affinity DataIC50: 1.86E+3nMAssay Description:Antagonist activity at human M4 receptor expressed in HEK293T cells assessed as inhibition of carbachol-induced response by BRET based Gq protein act...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Universit£ di Camerino
Curated by ChEMBL
Universit£ di Camerino
Curated by ChEMBL
Affinity DataEC50: 19nMAssay Description:Agonist activity at human M4 receptor expressed in HEK293T cells by BRET based Gq protein engagement assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Universit£ di Camerino
Curated by ChEMBL
Universit£ di Camerino
Curated by ChEMBL
Affinity DataEC50: 35nMAssay Description:Agonist activity at human M4 receptor expressed in HEK293T cells by BRET based Gq protein activation assayMore data for this Ligand-Target Pair
