Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Myeloperoxidase' and Ligand = 'BDBM312245'
TargetMyeloperoxidase(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM312245(1-{4-Chloro-2-[(methylamino)methyl]benzyl}-2-thiox...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:The pharmacological activity of compounds disclosed herein was tested in the following screen (Test A) in which the compounds were tested in the pres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q24296US Patent
TargetMyeloperoxidase(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM312245(1-{4-Chloro-2-[(methylamino)methyl]benzyl}-2-thiox...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:MPO: The pharmacological activity of compounds disclosed herein was tested in the following screen (Test A) in which the compounds were tested in the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WW7M2NUS Patent
TargetMyeloperoxidase(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM312245(1-{4-Chloro-2-[(methylamino)methyl]benzyl}-2-thiox...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Methods for the determination of MPO inhibitory activity are disclosed in WO 02/090575. The pharmacological activity of compounds disclosed herein wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7MD4US Patent
TargetMyeloperoxidase(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM312245(1-{4-Chloro-2-[(methylamino)methyl]benzyl}-2-thiox...)copy SMILEScopy InChI
Affinity DataIC50: 16nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44KMPubMed
TargetMyeloperoxidase(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM312245(1-{4-Chloro-2-[(methylamino)methyl]benzyl}-2-thiox...)copy SMILEScopy InChI
Affinity DataIC50: 6.60E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44KMPubMed