Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'N-glycosylase/DNA lyase' and Ligand = 'BDBM163681'
TargetN-glycosylase/DNA lyase(Homo sapiens (Human))
Oregon Health & Science University

LigandPNGBDBM163681(3-Chloro‐N'‐[(1E)‐(4‐f...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Gel-based assays were performed by combining 4 無 of OGG1 (62.5 nM) with 1 無 of inhibitor or buffer. Substrate (5 無, 50 nM) was added to bring the ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7M6HPubMed
TargetN-glycosylase/DNA lyase(Homo sapiens (Human))
Oregon Health & Science University

LigandPNGBDBM163681(3-Chloro‐N'‐[(1E)‐(4‐f...)copy SMILEScopy InChI
Affinity DataIC50: 420nMpH: 7.5 T: 2°CAssay Description:A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7M6HPubMed