Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'NAD-dependent protein deacetylase sirtuin-1' and Ligand = 'BDBM50168918'
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50168918(CHEMBL3806063)copy SMILEScopy InChI
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of human recombinant SIRT1 expressed in Escherichia coli BL21(DE3) cells using Ac-RHK-K(Ac)-AMC as substrate preincubated for 10 mins foll...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z89F9WPubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50168918(CHEMBL3806063)copy SMILEScopy InChI
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT1 (1 to 747 residues) expressed in Escherichia coli using Ac-RHK-K(Ac)-AMC as substrate inc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z89F9WPubMed