Found 3 Enz. Inhib. hit(s) with Target = 'NAD-dependent protein deacetylase sirtuin-2' and Ligand = 'BDBM50148776' TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University of Freiburg
Curated by ChEMBL
University of Freiburg
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human sirtuin 2 (25 to 389 residues) assessed as inhibition of substrate deacetylation using ZMAL as substrate incubated for 4 hrs by f...More data for this Ligand-Target Pair
3D Structure (crystal)TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University of Freiburg
Curated by ChEMBL
University of Freiburg
Curated by ChEMBL
Affinity DataIC50: 3.75E+3nMAssay Description:Inhibition of N-terminal his6-tagged human SIRT2 (25 to 389 amino acids) using ZMAL as substrate after 4 hrs by fluorescence-based microplate reader ...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University of Freiburg
Curated by ChEMBL
University of Freiburg
Curated by ChEMBL
Affinity DataIC50: 3.75E+3nMAssay Description:Inhibition of recombinant human His10-tagged Sirt2 (56 to 356 residues) expressed in Escherichia coli BL21(DE3) using Z-(Ac)Lys-AMC as substrate meas...More data for this Ligand-Target Pair
