Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'NT-3 growth factor receptor' and Ligand = 'BDBM50507492'
TargetNT-3 growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50507492(Loxo-195 | Selitrectinib | US10966985, Compound 33...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of TrKC (unknown origin) incubated for 120 mins in presence of 33P-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6H3KPubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50507492(Loxo-195 | Selitrectinib | US10966985, Compound 33...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of wild-type TrKC (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6H3KPubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50507492(Loxo-195 | Selitrectinib | US10966985, Compound 33...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP868WPubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50507492(Loxo-195 | Selitrectinib | US10966985, Compound 33...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of wild type TrkC (unknown origin) using poly(Glu: Tyr) as substrate preincubated for 15 mins followed by substrate addition and further i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2377DMNPubMed