Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7' and Ligand = 'BDBM50096713'
TargetNeuronal acetylcholine receptor subunit alpha-7(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50096713(1H-Indole-3-carboxylic acid 1-aza-bicyclo[2.2.2]oc...)copy SMILEScopy InChI
Affinity DataKi:  2.30nMAssay Description:In vitro Binding affinity towards alpha-7 nAChR was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2028S36PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50096713(1H-Indole-3-carboxylic acid 1-aza-bicyclo[2.2.2]oc...)copy SMILEScopy InChI
Affinity DataEC50:  580nMAssay Description:Effective concentration that causes inhibition of alpha-7 nAChR, was determined. Values are expressed as EC50 +/- SEM.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2028S36PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£ d'Orl£ans

Curated by ChEMBL
LigandPNGBDBM50096713(1H-Indole-3-carboxylic acid 1-aza-bicyclo[2.2.2]oc...)copy SMILEScopy InChI
Affinity DataEC50:  580nMAssay Description:Partial agonist activity at rat alpha-7 nicotinic acetylcholine receptor expressed in Xenopus oocytes assessed as induction of currentsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC058KPubMed