Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7' and Ligand = 'BDBM50190783'
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Targacept, Inc

Curated by ChEMBL
LigandPNGBDBM50190783(CHEMBL379302 | N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl...)copy SMILEScopy InChI
Affinity DataKi:  12.5nMAssay Description:Binding affinity to alpha7 nAChRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P32QPPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Pfizer Global Research & Development

Curated by ChEMBL
LigandPNGBDBM50190783(CHEMBL379302 | N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl...)copy SMILEScopy InChI
Affinity DataKi:  12.5nMAssay Description:Displacement of [3H]MLA from alpha7 nAChR in Sprague-Dawley rat brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25B023SPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Targacept, Inc

Curated by ChEMBL
LigandPNGBDBM50190783(CHEMBL379302 | N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl...)copy SMILEScopy InChI
Affinity DataEC50:  86nMAssay Description:Agonist activity at alpha7 nAChRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P32QPPubMed