Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7' and Ligand = 'BDBM50264117'
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Targacept Inc

Curated by ChEMBL
LigandPNGBDBM50264117(3-[1-(4-Hydroxy-2-methoxy-phenyl)-meth-(E)-ylidene...)copy SMILEScopy InChI
Affinity DataKi:  420nMAssay Description:Displacement of [3H]-methyllycaconitine from alpha7 nAChR in rat hippocampal membranes after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q4DPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Targacept Inc

Curated by ChEMBL
LigandPNGBDBM50264117(3-[1-(4-Hydroxy-2-methoxy-phenyl)-meth-(E)-ylidene...)copy SMILEScopy InChI
Affinity DataKi:  620nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in rat brain membrane after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081M9PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Targacept Inc

Curated by ChEMBL
LigandPNGBDBM50264117(3-[1-(4-Hydroxy-2-methoxy-phenyl)-meth-(E)-ylidene...)copy SMILEScopy InChI
Affinity DataKi:  620nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in rat brain membrane after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081M9PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50264117(3-[1-(4-Hydroxy-2-methoxy-phenyl)-meth-(E)-ylidene...)copy SMILEScopy InChI
Affinity DataKd:  23nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ88JPPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Targacept Inc

Curated by ChEMBL
LigandPNGBDBM50264117(3-[1-(4-Hydroxy-2-methoxy-phenyl)-meth-(E)-ylidene...)copy SMILEScopy InChI
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at rat recombinant alpha7 nAChR expressed in GH4C1 cells by patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q4DPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50264117(3-[1-(4-Hydroxy-2-methoxy-phenyl)-meth-(E)-ylidene...)copy SMILEScopy InChI
Affinity DataEC50:  3.00E+3nMAssay Description:Agonist activity at human cloned wild-type alpha7 nAChR expressed in Xenopus laevis oocytes assessed as channel opening by voltage clamp electrophysi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ88JPPubMed