Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Neutrophil collagenase' and Ligand = 'BDBM445058'
TargetNeutrophil collagenase(Homo sapiens (Human))TBA
LigandPNGBDBM445058(US10669227, Compound 1 | US11608309, Compound 1)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMAssay Description:Table 1 shows the IC50 of curcumin, compound 1, and compound 2, compared to a standard Zn++ binding & MMPI (matrix metalloproteinase inhibitor), 1,10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent
TargetNeutrophil collagenase(Homo sapiens (Human))TBA
LigandPNGBDBM445058(US10669227, Compound 1 | US11608309, Compound 1)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5X14US Patent