Compile Data Set for Download or QSAR
Found 11 Enz. Inhib. hit(s) with Target = 'Nitric oxide synthase, brain' and Ligand = 'BDBM50063300'
TargetNitric oxide synthase, brain(Homo sapiens (Human))
AstraZeneca R& D Charnwood

Curated by ChEMBL
LigandPNGBDBM50063300((L-N6-1-iminoethyl)lysine | (S)-6-Acetimidoylamino...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory activity against human neuronal nitiric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75H3MPubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50063300((L-N6-1-iminoethyl)lysine | (S)-6-Acetimidoylamino...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by neuronal NOS (n NOS) from rat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
AstraZeneca R& D Charnwood

Curated by ChEMBL
LigandPNGBDBM50063300((L-N6-1-iminoethyl)lysine | (S)-6-Acetimidoylamino...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:In vitro inhibition of human neuronal nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M656DPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
AstraZeneca R& D Charnwood

Curated by ChEMBL
LigandPNGBDBM50063300((L-N6-1-iminoethyl)lysine | (S)-6-Acetimidoylamino...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human nNOS expressed in insect SF9 cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9961QPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
AstraZeneca R& D Charnwood

Curated by ChEMBL
LigandPNGBDBM50063300((L-N6-1-iminoethyl)lysine | (S)-6-Acetimidoylamino...)copy SMILEScopy InChI
Affinity DataIC50: 1.75E+4nMAssay Description:Inhibitory activity against Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q218377VPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
AstraZeneca R& D Charnwood

Curated by ChEMBL
LigandPNGBDBM50063300((L-N6-1-iminoethyl)lysine | (S)-6-Acetimidoylamino...)copy SMILEScopy InChI
Affinity DataIC50: 1.84E+4nMAssay Description:Inhibitory activity against neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319V30PubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
AstraZeneca R& D Charnwood

Curated by ChEMBL
LigandPNGBDBM50063300((L-N6-1-iminoethyl)lysine | (S)-6-Acetimidoylamino...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMAssay Description:The concentration required for inhibition of Human Neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2445N74PubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
AstraZeneca R& D Charnwood

Curated by ChEMBL
LigandPNGBDBM50063300((L-N6-1-iminoethyl)lysine | (S)-6-Acetimidoylamino...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition concentration against Neuronal nitric oxide synthase (nNOS) at 10 uM concentrationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B60WXPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
AstraZeneca R& D Charnwood

Curated by ChEMBL
LigandPNGBDBM50063300((L-N6-1-iminoethyl)lysine | (S)-6-Acetimidoylamino...)copy SMILEScopy InChI
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q261110MPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
AstraZeneca R& D Charnwood

Curated by ChEMBL
LigandPNGBDBM50063300((L-N6-1-iminoethyl)lysine | (S)-6-Acetimidoylamino...)copy SMILEScopy InChI
Affinity DataIC50: 6.10E+4nMAssay Description:Compound was evaluated for the Inhibition of Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ31TXPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
AstraZeneca R& D Charnwood

Curated by ChEMBL
LigandPNGBDBM50063300((L-N6-1-iminoethyl)lysine | (S)-6-Acetimidoylamino...)copy SMILEScopy InChI
Affinity DataIC50: 6.17E+4nMAssay Description:Inhibition of human nNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H996GJPubMed