Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Nitric oxide synthase, brain' and Ligand = 'BDBM50086467'
TargetNitric oxide synthase, brain(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50086467((S)-4-(2-Acetimidoylamino-ethylsulfanyl)-2-amino-b...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:In vitro inhibition of human neuronal nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M656DPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50086467((S)-4-(2-Acetimidoylamino-ethylsulfanyl)-2-amino-b...)copy SMILEScopy InChI
Affinity DataIC50: 1.45E+5nMAssay Description:Inhibition of human nNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H996GJPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50086467((S)-4-(2-Acetimidoylamino-ethylsulfanyl)-2-amino-b...)copy SMILEScopy InChI
Affinity DataIC50: 1.45E+5nMAssay Description:Inhibition of human neuronal Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C1XDNPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50086467((S)-4-(2-Acetimidoylamino-ethylsulfanyl)-2-amino-b...)copy SMILEScopy InChI
Affinity DataIC50: 1.45E+5nMAssay Description:Inhibition of human recombinant nNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB538TPubMed