Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Nitric oxide synthase, inducible' and Ligand = 'BDBM50014711'
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50014711(CHEMBL3262020 | US10759791, Compound 5S | US995101...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of purified mouse iNOS assessed as inhibition of nitric oxide-mediated oxidation of hemoglobin-A by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6S26PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50014711(CHEMBL3262020 | US10759791, Compound 5S | US995101...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Enzyme inhibition was evaluated by measuring NO production with the hemoglobin capture assay, which was performed with purified NOSs in 96-well plate...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1PZGUS Patent
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astex

LigandPNGBDBM50014711(CHEMBL3262020 | US10759791, Compound 5S | US995101...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:The NOSs isoform assays involved subjecting 3-8 to an oxyhemoglobin NO capture assay using a Biotek Gen5™ microplate reader. IC50 values for each com...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N83G1US Patent