Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Nitric oxide synthase, inducible' and Ligand = 'BDBM50098939'
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098939(3-Thiazol-2-yl-3,4-dihydro-isoquinolin-1-ylamine |...)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+3nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by inducible NOS (i NOS) from human DLD-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098939(3-Thiazol-2-yl-3,4-dihydro-isoquinolin-1-ylamine |...)copy SMILEScopy InChI
Affinity DataIC50: 8.80E+8nMAssay Description:Inhibitory concentration against nitric oxide synthesis in intact DLD-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed