Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Non-receptor tyrosine-protein kinase TYK2' and Ligand = 'BDBM50565964'
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))TBA
LigandPNGBDBM50565964(CHEMBL4788122)copy SMILES
Affinity DataIC50: 1.40nMAssay Description:Inhibition of TYK2 JH2 domain (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4PJXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))TBA
LigandPNGBDBM50565964(CHEMBL4788122)copy SMILES
Affinity DataIC50: 69nMAssay Description:Inhibition of TYK2 in IFN-alpha stimulated human Kit225 T cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4PJXPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))TBA
LigandPNGBDBM50565964(CHEMBL4788122)copy SMILES
Affinity DataIC50: 183nMAssay Description:Inhibition of TYK2 in human whole blood assessed as decrease in IFNalpha-induced STAT5 phosphorylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4PJXPubMed