Found 2 Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-beta' and Ligand = 'BDBM50466891' TargetNuclear receptor ROR-beta(Homo sapiens (Human))
Karo Bio AB (now Karo Pharma AB)
Curated by ChEMBL
Karo Bio AB (now Karo Pharma AB)
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inverse agonist activity at RORB (unknown origin) assessed as inhibition of biotinylated co-activator SRC1-2 peptide recruitment after 3 hrs by TR-FR...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-beta(Homo sapiens (Human))
Karo Bio AB (now Karo Pharma AB)
Curated by ChEMBL
Karo Bio AB (now Karo Pharma AB)
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inverse agonist activity at GAL4-fused RORB LBD (unknown origin) expressed in mouse neuro2A cells assessed as inhibition of transcriptional activity ...More data for this Ligand-Target Pair
